Publications majeures de l'Equipe 5 [Dymec]

Dynamique du Micro-Environment et Cancer [Dymec]

  • BELLAMRI M, LE HEGARAT L, TURESKY RJ and LANGOUËT S. Metabolism of the Tobacco Carcinogen 2-Amino-9H-pyrido[2,3-b]indole (AαC) in Primary Human Hepatocytes. Chem Res Toxicol, 2017, 30, 657-668.
  • SAMAL SS, NALDI A, GRIGORIEV D, WEBER A, THÉRET N, RADULESCU O. Geometric analysis of pathways dynamics: Application to versatility of TGF-β receptors. Biosystems. 2016 Nov;149:3-14.
  • BOMO J, EZAN F, TIAHO F, ROUEDE D, FAUTREL A, LANGOUËT S, THERET N and BAFFET G. Stiffness strengthens proliferation and motility of human liver cells in 3D collagen matrices through the MEK/ERK and MLCK pathways. J Cell Biochem, 2015, 9999, 1-13.
  • RUFF M, LEYME A, LE CANN F, BONNIER D, LE SEYEC J, CHESNEL F, FATTET L, RIMOKH R, BAFFET G, THERET N. The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition. PLoS One. 2015
  • NIZARD P, EZAN F, BONNIER D, LE MEUR N, LANGOUËT S, BAFFET G, ARLOT-BONNEMAINS Y, THÉRET N. Integrative analysis of high-throughput RNAi screen data identifies the FER and CRKL tyrosine kinases as new regulators of the mitogenic ERKdependent  pathways in transformed cells. BMC Genomics. 2014 Dec 23;15:1169.
  • NAUWELAËRS G, BELLAMRI M, FESSARD V, TURESKY RJ, LANGOUËT S. DNA adducts of the tobacco carcinogens 2-amino-9Hpyrido[2,3-b]indole and 4-aminobiphenyl are formed at environmental exposure levels and persist in human hepatocytes. Chem Res Toxicol. 2013;16;26(9):1367-77
  • FRÉMIN C, EZAN F, GUEGAN JP, GAILLOUSTE L, TROTARD M, SEYEC JL, THÉRET N, LANGOUËT S, BAFFET G. The complexity of ERK1 and ERK2 MAPKs in multiple hepatocyte fate responses. J Cell Physiol. 2012;227(1):59-69.
  • BOURD-BOITTIN K, BONNIER D, LEYME A, MARI B, TUFFERY P, SAMSON M, EZAN F, BAFFET G, THERET N. Protease profiling of liver fibrosis reveals the ADAM metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of transforming growth factor beta. Hepatology. 2011: 54(6):2173-84
  • GAILHOUSTE L, LE GRAND Y, ODIN C, GUYADER D, TURLIN B, EZAN F, DÉSILLE Y, GUILBERT T, BESSARD A, FRÉMIN C, THÉRET N, BAFFET G. Fibrillar collagen scoring by second harmonic microscopy: a new tool in the assessment of liver fibrosis. J Hepatol. 2010 Mar;52(3):398-406.