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NEW! Offre de contrat doctoral (thèse) : Irset Rennes/Subatech Nantes

Approche "théranostique" de la maladie d'Alzheimer par des hexapeptides

"Theranostic" approach to Alzheimer's disease using hexapeptides

Type de contrat: CDD de 36 mois
Co-financement : Région de Bretagne/ IMT Atlantique
Debut du projet : 1er octobre 2022
Consulter le sujet de thèse: 

fiche sujet de thèse - (181.91 Ko)

Encadrants de thèse :

Co-directeurs (contact) :
Cyrille GARNIER, MCU-HDR Université de Rennes 1, irset, équipe DREAM, cyrille [dot] garnieratuniv-rennes1 [dot] fr 
Sandrine HUCLIER, MCU-HDR Nantes Université, Laboratoire Subatech, sandrine [dot] huclieratsubatech [dot] in2p3 [dot] fr 

Co-encadrant :
Vincent METIVIER, Laboratoire Subatech
vincent [dot] metivieratsubatech [dot] in2p3 [dot] fr 


Les candidats devront soumettre à Cyrille Garnier, avant le 13 juillet 2022, les documents suivants :
- Un curriculum vitae (intégrant le nom d'au moins une personne référente),
- Une lettre de motivation
- Une copie du rapport de Master 2

Après examen des dossiers, des auditions seront programmées en juillet 2022.

Offre d'emploi - Ingénieur.e de données SNDS - Equipe 11 - Drive

Poste à temps plein à pourvoir dès que possible 

La personne recrutée aura pour mission de renforcer l’axe 2 de l’équipe 11, au sein de l’équipe de pharmaco-épidémiologie. Dans le cadre de projets européens et nationaux, elle sera en charge de la partie gestion et analyse des données, en utilisant les données issues du système national des données de santé (SNDS). Mission réalisée sous la responsabilité des pharmaco-épidémiologistes impliqués dans divers projets de recherche de l’équipe DRIVE.

Visualiser la fiche de poste : Ingenieur.e données SNDS - (195.94 Ko)   - CDD 12 mois

Envoyer CV et lettre de motivation à Dr SCAILTEUX Lucie-Marie Lucie-marie [dot] scailteuxatuniv-rennes1 [dot] fr

 

NEW! Offre de contrat doctoral (thèse) : projet PHARE EHESP/Univ Marseille/LHN Anses

CDD de 36 mois

Poste à temps plein à pourvoir pour le 1er septembre 2022.

Consulter le sujet de thèse - (684.09 Ko)

Co-direction : EHESP / Université de Marseille / Anses-LHN

Encadrants de thèse :
- Marie-Florence Thomas, Professeure EHESP, marie-florence [dot] thomasatehesp [dot] fr
- Jean-Luc Boudenne, Professeur Université de Aix-Marseille, jean-luc [dot] boudenneatuniv-amu [dot] fr,
- Xavier Dauchy et Christophe Rosin, Chercheurs LHN-Anses, Xavier [dot] DAUCHYatanses [dot] fr ; Christophe [dot] ROSINatanses [dot] fr

Les candidats devront soumettre, avant le 30 avril 2022, les documents suivants :
- Un curriculum vitae (intégrant au moins le nom d’une personne référente),
- Une lettre de motivation,
- Une copie de son rapport de Master 2 (si disponible).

Après examen des dossiers, des auditions seront programmées en juin 2022.

PhD Thesis in Environmental Epidemiology

Prenatal exposure to environmental chemicals and cardiometabolic health in adolescents.

Host team
The Research Institute of Environmental and Occupational Health (Irset) is a joint research unit (UMR_S 1085) of Inserm, the University of Rennes 1 and the School of public Health (EHESP). Its mission is to study the biological processes and environmental factors that influence human health and to support the work of authorities concerned with public health. This PhD thesis will be carried out within the Elixir team (Lifecourse Epidemiology and exposure science in environmental health) and will be based at the EHESP campus in Rennes, in the Irset building.
 

Doctoral School
Doctoral School Biology-Health (BS, Biologie-Santé) from the Bretagne Loire University

Keywords
Epidemiology; Environment; Pregnancy; Chemicals; Biostatistics; Cardiometabolic health

Supervision
Dr Cécile Chevrier, Inserm Research director, Team leader

Dr Charline Warembourg, Inserm Researcher

PhD candidate profile

  • Master degree in Public health
  • Epidemiology or Biostatistics
  • Good statistical knowledge
  • Skills on R or SAS software
  • English
  • Interest in health and environment

Application procedure

Please send your CV and a motivation letter to charline [dot] warembourgatinserm [dot] fr before April, 22th 2022.

Fundings

PhD grant from the French Ministry of Research, Higher Education, and Innovation (‘’Contrat Doctoral
d’Etablissement’’): Irset internal selection in June 2022 (3 funded grants for 5 applying candidates)

Start of the PhD

Last trimester of 2022

More information : PhD thesis proposal Irset - (163.31 Ko) / (Version française : Sujet thèse Epidémiologie Irset - (167.85 Ko) )

Assistant-Professor in Biochemistry / HRMS-based Exposomics

Researcher profile: Young Researcher (with less than 4 years research experience after PhD) or Established Researcher (with more than 4 years research experience)

Research fields: Biological Science, Chemistry, Environmental Science, Medical Sciences 

Main Activities:

Research: Assessment of human exposure to environmental contaminants (chemical exposome)
Technological advances in high-resolution mass spectrometry (HRMS), combined with the development of innovative bioinformatics tools, allows to characterize on large scale and without any a priori human exposure to chemical mixtures. These novel approaches based on HRMS, called “non-targeted”, provide a unique opportunity to capture the exposome (i.e. the totality of environmental exposures of an individual in a lifetime), and particularly the chemical exposome.
This new paradigm for exposure measurement offers new perspectives in the field of environmental health. The strategy of Irset, and more particularly the ELIXIR team (Lifecourse Epidemiology and Exposure Science for Environmental Health Exposure) is to develop new research to better understand the links between environmental chemicals exposures and the occurrence of chronic diseases in large scale epidemiological studies. Irset aims, both at the University of Rennes and at the national (medical research) and European levels, to position this theme as a high priority.
Consequently, Irset offers a position of permanent assistant professor position. We are seeking candidates with excellent skills in analytical chemistry (and in particular in LC / GC-HRMS) and/or in bioinformatics (big data analysis) to join the ELIXIR team which has already developed projects in this new field of research linked to the chemical exposome.
Successful candidate will have a strong background in analytical metabolomics/exposomics and/or bioinformatics for mining HRMS data. He/she will thus be responsible for developing new analytical and/or bioinformatics methods to conduct projects based on non-targeted HRMS analysis, on a large scale, of biological samples from epidemiological cohorts. These projects will aim to characterize, on a broad spectrum, exposures to mixtures of environmental chemicals and to study the existing associations between these exposures and health outcomes of interest to the host team. Strong interactions are expected with the epidemiologists from the host team but also with other Irset researchers with expertise in toxicology and "omics" sciences. The candidate must demonstrate very good communication skills in English in order to teach in English and to interact regularly with foreign researchers.
Key-words: Biochemistry, Metabolic biochemistry, Omics, bioinformatics

Teaching: Teaching general and analytical biochemistry as well as metabolism (French and English) to undergraduated students. Experience using omics techniques and integrated dimension of biochemistry, as well as research assessment of human exposure to environmental contaminants, especially environmental chemicals, in order to build Master degree teaching in the field. 

Required Experience: 2 to 10 years  

Fields: Biochemistry, Metabolic biochemistry, Omics, bioinformatics

Required Education Level or Diploma: PhD

Required Languages: French, English

Hosting Unit:
- Teaching (on Rennes Beaulieu campus): University of Rennes 1, Faculty of Life and environmental sciences (Director: Claire Piquet-Pellorce). 2,800 students in life and environmental sciences, 120 lecturers, 20 persons for administrative and technical assistance. 
www.sve.univ-rennes1.fr
- Research (on Rennes Villejean campus): Institut de recherche en santé, environnement et travail (Irset, UMR_S 1085) (Research Institute for Environmental and Occupational Health). Close to 350 persons, 11 research teams, and 1 technology platform
www.irset.org

Type: permanent contract

Duration: Permanent

Salary: According to experience

Envisaged Start Date: September 1, 2022

Application: Applicants should confirm their application by sending their CV to: Yves Le Dréan (Yves [dot] le-dreanatuniv-rennes1 [dot] fr) and Arthur David (arthur [dot] davidatehesp [dot] fr)

Deadline for application: 31 March 2022