Team C. Pineau | Cellular and Molecular Actors of the Reproductive Function (COCOON)

The team led by Charles Pineau has expertise in the field of human reproduction, from the differentiation of the Hypothalamic-Pituito-Gonadic axis, the production, maturation, interaction of gametes to embryonic development. In this context, the team is also exploring the effects of environmental and chemical molecules on the reproductive system.

The COCOON team articulates its work around 5 areas of research:

  • Differentiation of the Hypothalamo-Pituito-Gonadic axis
  • Proteomes of the male and female genital spheres
  • Post-testicular sperm maturation
  • Development and function of the oviduct in the early stages of embryonic development
  • Impact of small molecules on the male and female reproductive systems
Image en immunofluorescence of an adult Zebrafish brain Tyrosine hydroxylase (red) PCNA (green) nuclei (blue)

Axis 1 | Differentiation of the Hypothalamic-Pituitary-Gonadal (HPG) axis

Axis 2 | Proteomes of the male and female genital spheres

Axis 3 | Post-testicular sperm maturation

Axis 4 | Development and function of the oviduct during the early stage of embryo development

Axis 5 | Impact of small molecules on the male and female reproductive systems