Research Fields

Irset is, in Europe, one of the largest national inter- and multi-disciplinary research centers on environmental and occupational health.

Research at Irset

Irset's research work ranges from the identification of specific hazards to exposure measurement. It also aims to characterize the effects of those hazards on animals and human beings, and to study how they can cause and/or worsen certain pathologies. Our knowledge of the effect on our health of many environmental factors, in the air we breathe, the food we eat, and the places in which we live and work, remains very limited.

This multi-faceted approach requires a completely unprecedented continuum between :

  • fundamental research,
  • clinical research,
  • methodological research,
  • toxicology,
  • epidemiology,
  • risk evaluation,
  • expertise,
  • interaction with the general public.


Irset's research topics centre on environmental stress, infection, signalling, cancerogenesis, endocrinology, reproduction and development, epidemiology, the exposome, genomics, systems biology and toxicology.

Fundamental and clinical research

The Institute's research teams conduct both fundamental and clinical studies on various pathologies :

  • Prostate, breast, lung, liver, testicular, kidney, upper respiratory tract cancers ;
  • Pulmonary diseases: COPD, cystic fibrosis ;
  • Infectious diseases: hepatitis, Aids, Zika ;
  • Developmental and reproductive pathologies.