Dernières publications majeures de l'équipe TREC

Publications récentes de l'équipe " Transcription, environnement et cancer " dirigée par Farzad PAKDEL

  • 2019
  • Lecomte S, Demay F, Pham TH, Moulis S, Efstathiou T, Chalmel F, Pakdel F (2019) Deciphering the Molecular Mechanisms Sustaining the Estrogenic Activity of the Two Major Dietary Compounds Zearalenone and Apigenin in ER-Positive Breast Cancer Cell Lines. Nutrients, 11, 237.
  • Pham T.H., Lecomte S., Efstathiou T., Ferriere F., Pakdel F (2019) An Update on the Effects of Glyceollins on Human Health: Possible Anticancer Effects and Underlying Mechanisms. Nutrients, 11, 79.
  • 2018
  • Pakdel F (2018) Molecular Pathways of Estrogen Receptor Action. Int J Mol Sci., 19, 2591
  • Hinfray N, Tebby C, Piccini B, Bourgine G, Aït-Aïssa S, Porcher JM, Pakdel F, Brion F (2018) Mixture Concentration-Response Modeling Reveals Antagonistic Effects of Estradiol and Genistein in Combination on Brain Aromatase Gene (cyp19a1b) in Zebrafish. Int J Mol Sci. 2018 Apr 1;19(4).
  • Cacialli P, D'angelo L, Kah O, Coumailleau P, Gueguen MM, Pellegrini E, Lucini C (2018)Neuronal expression of brain derived neurotrophic factor in the injured telencephalon of adult zebrafish. J Comp Neurol.1;526(4):569-582. doi: 10.1002/cne.24352. Epub 2017 Nov 26.
  • Gemmel M, Bögi E, Ragan C, Hazlett M, Dubovicky M, van den Hove DL, Oberlander TF, Charlier TD, Pawluski JL (2018) Perinatal selective serotonin reuptake inhibitor medication (SSRI) effects on social behaviors, neurodevelopment and the epigenome. Neurosci Biobehav Rev. 85:102-116. doi: 10.1016/j.neubiorev.2017.04.023.
  • Gemmel M, Harmeyer D, Bögi E, Fillet M, Hill LA, Hammond GL, Charlier TD, Pawluski JL (2018). Perinatal fluoxetine increases hippocampal neurogenesis and reverses the lasting effects of pre-gestational stress on serum corticosterone, but not on maternal behavior, in the rat dam. Behav Brain Res.  26;339:222-231. doi: 10.1016/j.bbr.2017.11.038
  • 2017
  • Lecomte S, Habauzit D, Charlier T.D, Pakdel F. Emerging Estrogenic Pollutants in the Aquatic Environment and Breast Cancer. (2017) Genes 2017, 8, 229.
  • Lecomte S, Chalmel F, Ferriere F, Percevault F, Plu N, Saligaut C, Surel C, Le Long M, Efstathiou T, Pakdel F (2017) Glyceollins trigger anti-proliferative effects through estradiol-dependent and independent pathways in breast cancer cells. Cell Communication and Signaling, 15: 26.
  • Lecomte S, Demay F, Ferriere F, Pakdel F (2017) Phytochemicals targeting estrogen receptors: beneficial rather than adverse effects? Int J Mol Sci., 18, 1381.
  • Lecomte S, Le Long M, Bourgine G, Efstathiou T, Saligaut C, Pakdel F (2017) Assessment of the potential activity of major dietary compounds as selective estrogen receptor modulators in two distinct cell models for proliferation and differentiation. Toxicol Appl Pharmacol, 325:61-70.
  • Habauzit D, Martin C, Kerdivel G, Pakdel F (2017) Rapid assessment of estrogenic compounds by CXCL-test illustrated by the screening of the UV-filter derivative Benzophenone (BP). Chemosphere, 173: 253-260.
  • Haas AJ, Le Page Y, Zhadobov M, Sauleau R, Le Drean Y, Saligaut C (2017) Effect of acute millimeter wave exposure on dopamine metabolism of NGF-treated PC12 cells. J Radiat Res, 58,  439-445.
  • 2016
  • Jehanno C, Flouriot G, Le Goff P, Michel D (2016) A model of dynamic stability of H3K9me3 heterochromatin to explain the resistance to reprogramming of differentiated cells. Biochim. Biophys. Acta. Gene Regulatory Mechanisms , 1860, 184-195.
  • Chouchene L, Pellegrini E, Gueguen MM, Hinfray N, Brion F, Piccini B, Kah O, Saïd K, Messaoudi I, Pakdel F (2016) Inhibitory effect of Cadmium on estrogen signaling in zebrafish brain and protection by Zinc. J Appl Toxicol, 2016, 36: 863-871.
  • Jehanno C, Flouriot G, Nicol-Benoît F, Le Page Y, Le Goff P, Michel D (2016) Envisioning metastasis as a transdifferentiation phenomenon clarifies discordant results on cancer. Breast Dis., 36:47-59.
  • 2014
  • Flouriot G., Huet G., Demay F., Pakdel F., Boujrad N., Michel D (2014) The actin/MKL1 signaling pathway influences cell growth and gene expression through large-scale chromatin reorganization and histone post-translational modifications. Biochem. J., 461:257-68.
  • Kerdivel G, Boudot A, Habauzit D, Percevault F, Demay F, Pakdel F, Flouriot G (2014) Activation of the MKL1/actin signaling pathway induces hormonal escape in estrogen-responsive breast cancer cell lines. Mol Cell Endocrinol, 390:34-44.
  • Boudot A, Kerdivel G, Lecomte S, Flouriot G, Desille M, Godey F, Leveque J, Tas P, Le Dréan Y, Pakdel F (2014) COUP-TFI modifies CXCL12 and CXCR4 expression by activating EGF signaling and stimulates breast cancer cell migration. BMC Cancer, 14:407.
  • Habauzit D., Ferrière F., Botherel N., Flouriot G., Pakdel F., Saligaut C (2014) Differentiation of PC12 cells expressing estrogen receptor alpha: a new bioassay for endocrine-disrupting chemicals evaluation. Chemosphere, 112, 240-247.

Publications des membres de l'équipe 6 sur Pubmed

Farzad Pakdel
Gilles Flouriot
Yves Le Drean
Thierry Charlier