-M Boutet, L Gauthier, M Leclerc, G Gros, V de Montpreville, N Théret, E Donnadieu, F Mami-Chouaib. TGF-β signaling intersects with CD103 integrin signaling to promote T lymphocyte accumulation and antitumor activity in the lung tumor microenvironment. Cancer Res , in press

-Cousin FJ, Jouan-Lanhouet S, Théret N, Brenner C, Jouan E, Le Moigne-Muller G, Dimanche-Boitrel MT, Jan G. The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer. Oncotarget. 2016 Jan 11.

-Bomo J, Ezan F, Tiaho F, Bellamri M, Langouët S, Theret N, Baffet G.Increasing 3D Matrix Rigidity Strengthens Proliferation and Spheroid Development of Human Liver Cells in a Constant Growth Factor Environment. J Cell Biochem. 2016 Mar;117(3):708-720.

– Ruff M, Leyme A, Le Cann F, Bonnier D, Le Seyec J, Chesnel F, Fattet L, Rimokh R, Baffet G, Théret N. The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition. PLoS One. 2015 Sep 25;10(9).

-Pathak K, Bellamri M, Wang Y, Langouët S and Turesky RJ. Characterization of serum albumin addcuts and cysteine and methionine oxidative stress markers, by the tobacco carcinogen 2-Amino-9H-pyrido[2,3-b]indole (AaC), in human hepatocytes, J Biol Chem, 290, 16304-16318.

-Wang Y, Peng L., Bellamri M, Langouët S and Turesky RJ. Mass Spectrometric Characterization of human serum albumin adducts formed with N-oxidized metabolites of 2-Amino-1-methyl-phenylimidazo[4,5-b]pyridine in human plasma and hepatocytes, Chem Res Toxicol, 28, 1045-1059.

-Rouede D, Bellanger JJ, Bomo J, Baffet G, Tiaho F. Linear least square (LLS) method for analysis of polarization SHG images of collagen fibrils. Opt Express 2015.

-Edmond V, Dufour F, Poiroux G, Shoji K, Malleter M, Fouqué A, Tauzin S, Rimokh R, Sergent O, Penna A, Dupuy A, Levade T, Théret N, Micheau O, Ségui B, Legembre P. Downregulation of ceramide synthase-6 during epithelial-to-mesenchymal transition reduces plasma membrane fluidity and cancer cell motility. Oncogene. 2015 Feb 19;34(8):996-1005.

-Recher G, Coumailleau P, Rouède D, Tiaho F. Structural origin of the drastic modification of second harmonic generation intensity pattern occurring in tail muscles of climax stages xenopus tadpoles. J Struct Biol. 2015, 190(1): 1-10.


-Nizard P, Ezan F, Bonnier D, Le Meur N, Langouët S, Baffet G, Arlot-Bonnemains Y, Théret N. Integrative analysis of high-throughput RNAi screen data identifies the FER and CRKL tyrosine kinases as new regulators of the mitogenic ERK-dependent pathways in transformed cells. BMC Genomics. 2014 Dec 23;15:1169.

-Andrieux G, Le Borgne M, Théret N. An integrative modeling framework reveals plasticity of TGF-β signaling. BMC Syst Biol. 2014, 12;8:30.

-Juin A, Di Martino J, Leitinger B, Henriet E, Gary AS, Paysan L, Bomo J, Baffet G, Gauthier-Rouvière C, Rosenbaum J, Moreau V, Saltel F. Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42-Tuba pathway. J Cell Biol. 2014, 24;207(4):517-33.

-Guégan JP, Ezan F, Gailhouste L, Langouët S, Baffet G.MEK1/2 overactivation can promote growth arrest by mediating ERK1/2-dependent phosphorylation of p70S6K. J Cell Physiol. 2014, 229(7):903-15.

-Rouède D., Coumailleau P., Schaub E., Bellanger J.-J., Blanchard-Desce M., Tiaho F. (2014). Myofibrillar misalignment correlated to triad disappearance of mdx mouse gastrocnemius muscle probed by SHG microscopy. Biomedical optics express, 5(3):858-875.



-Guégan JP, Ezan F, Théret N, Langouët S, Baffet G. MAPK signaling in cisplatin-induced death: predominant role of ERK1 over ERK2 in human hepatocellular carcinoma cells. Carcinogenesis. 2013, 34(1):38-47.

-Nauwelaërs G, Bellamri M, Fessard V, Turesky RJ, Langouët S. DNA adducts of the tobacco carcinogens 2-amino-9H-pyrido[2,3-b]indole and 4-aminobiphenyl are formed at environmental exposure levels and persist in human hepatocytes. Chem Res Toxicol. 2013;16;26(9):1367-77.

-Rouède D., Bellanger J.-J., Recher G., Tiaho F. (2013). Study of the effect of myofibrillar misalignment on the sarcomeric SHG intensity pattern. Optics Express, 21(9):11404-11414.

-Rouède D., Bellanger J.-J., Schaub E., Recher G., Tiaho F. (2013). Theoretical and Experimental SHG Angular Intensity Patterns from Healthy and Proteolysed Muscles. Biophysical Journal, 104(9):1959-68.



-Leyme A, Bourd-Boittin K, Bonnier D, Falconer A, Arlot-Bonnemains Y, Théret N. Identification Of Ilk As A New Partner Of The Adam12 Disintegrin And Metalloprotease In Cell Adhesion And Survival. Mol Biol Cell. 2012;23(17):3461-72.

-Alisi A, Baffet G. Self-renewal of tumor-initiating cells: what’s new about hepatocellular carcinoma? Gastroenterology. 2012,142(7):1414-6.

-Andrieux G, Fattet L, Le Borgne M, Rimokh R, Théret N. Dynamic regulation of TGF-b signaling by tif1γ: a computational approach. PLOS ONE. 2012;7(3).

-Follet J, Corcos L, Baffet G, Ezan F, Morel F, Simon B, Le Jossic-Corcos C. The association of statins and taxanes: an efficient combination trigger of cancer cell apoptosis. Br J Cancer. 2012;106(4):685-92.

-Tang Y, Lemaster Dm, Nauwelaërs G, Gu D, Langouët S, Turesky Rj. UDP-glucuronosyltransferase-mediated metabolic activation of the tobacco carcinogen 2-amino-9H-pyrido[2,3-b]indole. J Biol Chem. 2012;287(18):14960-72.

-Gu D, Turesky RJ, Tao Y, Langouët SA, Nauwelaërs GC, Yuan Jm, Yee D, Yu Mc. DNA adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 4-aminobiphenyl are infrequently detected in human mammary tissue by liquid chromatography/tandem mass spectrometry. Carcinogenesis. 2012;33(1):124-30.

-Frémin C, Ezan F, Guegan JP, Gaillouste L, Trotard M, Seyec Jl, Théret N, Langouët S, Baffet G. The complexity of ERK1 and ERK2 MAPKs in multiple hepatocyte fate responses. J Cell Physiol. 2012;227(1):59-69.

-Monnier J, Boissan M, L’helgoualc’h A, Lacombe Ml, Turlin B, Zucman-Rossi J, Théret N, Piquet-Pellorce C, Samson M. CXCR7 is up-regulated in human and murine hepatocellular carcinoma and is specifically expressed by endothelial cells. Eur J Cancer. 2012;48(1):138-48.

-Arshad M. I., Piquet-Pellorce C., L’helgoualc’h A., Rauch M., Patrat-Delon S., Ezan F., Lucas-Clerc C., Nabti S., Lehuen A., Cubero F. J., Girard J.-P., Trautwein C., Samson M. (2012). TRAIL but not FasL and TNFα, regulates IL-33 expression in murine hepatocytes during acute hepatitis. Hepatology, 56(6):2353-62.



-Rageul J, Frémin C, Ezan F, Baffet G, Langouët S.The knock-down of ERCC1 but not of XPF causes multinucleation. DNA Repair (Amst). 2011;10(9):978-90.

-Nauwelaers G, Bessette Ee, Gu D, Tang Y, Rageul J, Fessard V, Yuan Jm, Yu Mc, Langouët S, Turesky Rj. DNA adduct formation of 4-aminobiphenyl and heterocyclic aromatic amines in human hepatocytes. Chem Res Toxicol. 2011;24(6):913-25.

-Fleury V, Al-Kilani A, Boryskina Op, Cornelissen Aj, Nguyen Th, Unbekandt M, Leroy L, Baffet G, Le Noble F, Sire O, Lahaye E, Burgaud V. Introducing the scanning air puff tonometer for biological studies. Phys Rev E Stat Nonlin Soft Matter Phys. 2010;81(2 Pt 1):021920.

-Gruel J, Leborgne M, Lemeur N, Théret N. Simple Shared Motifs (SSM) in conserved region of promoters: a new approach to identify co-regulation patterns. BMC Bioinformatics. 2011;12:365.

-Bourd-Boittin K, Bonnier D, Leyme A, Mari B, Tuffery P, Samson M, Ezan F, Baffet G, Théret N. Protease profiling of liver fibrosis reveals the ADAM metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of transforming growth factor beta. Hepatology. 2011: 54(6):2173-84.

-Gilot D, Le Meur N, Giudicelli F, Le Vee M, Lagadic-Gossmann D, Théret N, Fardel O. RNAi-based screening identifies kinases interfering with dioxin-mediated up-regulation of CYP1A1 activity. PLoS One. 2011; 29;6(3):e18261.

-Khan J., Ezan F., Crémet J.-Y., Fautrel A., Gilot D., Lambert M., Benaud C., Troadec M.-B., Prigent C. (2011). Overexpression of active Aurora-C kinase results in cell transformation and tumour formation. PLoS ONE, 6(10):e26512.

-Rouede D, Recher G, Bellanger JJ, Lavault MT, Schaub E, Tiaho F. Modeling of supramolecular centrosymmetry effect on sarcomeric SHG intensity pattern of skeletal muscles. Biophys J. 2011, (101):494-503.

-Recher G, Rouède D, Schaub E, Tiaho F. Skeletal muscle sarcomeric SHG patterns photo-conversion by femtosecond infrared laser. Biomed. Opt. Express. 2011a, (2):374-384.

-Recher G, Rouede D, Tascon C, D’Amico LA, Tiaho F. Double-band sarcomeric SHG pattern induced by adult skeletal muscles alteration during myofibrils preparation. J Microsc. 2011b, (241):207-211.



-Gailhouste L, Le Grand Y, Odin C, Guyader D, Turlin B, Ezan F, Désille Y, Guilbert T, Bessard A, Frémin C, Théret N, Baffet G. Fibrillar collagen scoring by second harmonic microscopy: a new tool in the assessment of liver fibrosis. J Hepatol. 2010 Mar;52(3):398-406.

-Marvie P, Lisbonne M, L’helgoualc’h A, Rauch M, Turlin B, Preisser L, Bourd-Boittin K, Théret N, Gascan H, Piquet-Pellorce C, Samson M. Interleukin-33 overexpression is associated with liver fibrosis in mice and humans.J Cell Mol Med. 2010,14(6B):1726-39.

-Tekpli X, Rivedal E, Gorria M, Landvik NE, Rissel M, Dimanche-Boitrel MT, Baffet G, Holme JA, Lagadic-Gossmann D. The B[a]P-increased intercellular communication via translocation of connexin-43 into gap junctions reduces apoptosis.Toxicol Appl Pharmacol. 2010,242(2):231-40.

-Gailhouste L, Ezan F, Bessard A, Frémin C, Rageul J, Langouët S, Baffet G. RNAi-mediated MEK1 knock-down prevents ERK1/2 activation and abolishes human hepatocarcinoma growth in vitro and in vivo. Int J Cancer. 2010, 126(6):1367-77.

-Ellero S, Chakhtoura G, Barreau C, Langouët S, Benelli C, Penicaud L, Beaune P, de Waziers I. Xenobiotic-metabolizing cytochromes p450 in human white adipose tissue: expression and induction. Drug Metab Dispos. 2010, 38(4):679-86.

-Piton A, Rauch C, Langouët S, Guillouzo A, Morel F. Involvement of pregnane X receptor in the regulation of CYP2B6 gene expression by oltipraz in human hepatocytes.Toxicol In Vitro. 2010, 24(2):452-9.

-Guilbert T., Odin C., Le Grand Y., Gailhouste L., Turlin B., Ezan F., Désille Y., Baffet G., Guyader D. (2010). A robust collagen scoring method for human liver fibrosis by second harmonic microscopy. Optics Express, 18(25):25794-807.