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Olivier Fardel, Philippe Deleval, Laurent Vernhet, Lydie Sparfel, Valérie Lecureur, Eric Le Ferrec, Stéphane Jouneau

PUBLICATIONS 2013

Jaguin M, Houlbert N, Fardel O, Lecureur V. Polarization profiles of human M-CSF-generated macrophages and comparison of M1-markers in classically activated macrophages from GM-CSF and M-CSF origin. Cell Immunol. 2013 Feb 4;281(1):51-61. [pubmed]

Kolasa E, Houlbert N, Balaguer P, Fardel O. AhR- and NF-κB-dependent induction of interleukin-6 by co-exposure to the environmental contaminant benzanthracene and the cytokine tumor necrosis factor-α in human mammary MCF-7 cells. Chem Biol Interact. 2013 Feb 8. doi:pii: S0009-2797(13)00008-2. 10.1016/j.cbi.2013.01.005. [Epub ahead of print] [pubmed]

Noel G, Le Vee M, Moreau A, Stieger B, Parmentier Y, Fardel O. Functional expression and regulation of drug transporters in monolayer- and sandwich-cultured mouse hepatocytes. Eur J Pharm Sci. 2013 Feb 6. doi:pii: S0928-0987(13)00054-7. 10.1016/j.ejps.2013.01.013. [Epub ahead of print] [pubmed]

Le Vee M, Jouan E, Stieger B, Fardel O. Differential regulation of drug transporter expression by all-trans retinoic acid in hepatoma HepaRG cells and human hepatocytes. Eur J Pharm Sci. 2013 Jan 23;48(4-5):767-774. [pubmed]

Fardel O. Cytokines as molecular targets for aryl hydrocarbon receptor ligands: implications for toxicity and xenobiotic detoxification. Expert Opin Drug Metab Toxicol. 2013 Feb;9(2):141-52. [pubmed]

Macoch M, Morzadec C, Fardel O, Vernhet L. Inorganic arsenic impairs differentiation and functions of human dendritic cells. Toxicol Appl Pharmacol. 2013 Jan 15;266(2):204-13. [pubmed]

Marie I, Josse S, Decaux O, Dominique S, Landron C, Roblot P, Jouneau S, Vittecoq O, Jouen F. Outcome of anti-PL12 positive patients with antisynthetase syndrome. Presse Med. 2013 Feb 18. doi:pii: S0755-4982(13)00020-1. 10.1016/j.lpm.2012.12.003. [Epub ahead of print] [pubmed]

Marie I, Josse S, Decaux O, Diot E, Landron C, Roblot P, Jouneau S, Hatron PY, Hachulla E, Vittecoq O, Menard JF, Jouen F, Dominique S. Clinical manifestations and outcome of anti-PL7 positive patients with antisynthetase syndrome. Eur J Intern Med. 2013 Jan 31. doi:pii: S0953-6205(13)00007-1. 10.1016/j.ejim.2013.01.002. [Epub ahead of print][pubmed]

Comarmond C, Pagnoux C, Khellaf M, Cordier JF, Hamidou M, Viallard JF, Maurier F, Jouneau S, Bienvenu B, Puéchal X, Aumaître O, Le Guenno G, Le Quellec A, Cevallos R, Fain O, Godeau B, Seror R, Dunogué B, Mahr A, Guilpain P, Cohen P, Aouba A, Mouthon L, Guillevin L; French Vasculitis Study Group. Eosinophilic granulomatosis with polyangiitis (Churg-Strauss): clinical characteristics and long-term followup of the 383 patients enrolled in the French Vasculitis Study Group cohort. Arthritis Rheum. 2013 Jan;65(1):270-81. doi: 10.1002/art.37721. [pubmed]

Fillatre P, Chevrier S, Revest M, Gacouin A, Jouneau S, Leroy H, Robert-Gangneux F, Minjolle S, Le Tulzo Y, Tattevin P. Human herpes virus co-infection is associated with mortality in HIV-negative patients with Pneumocystis jirovecii pneumonia. Eur J Clin Microbiol Infect Dis. 2013 Feb;32(2):189-94. [pubmed]

Jouneau S, Kerjouan M, Caulet-Maugendre S, Guillot S, Meunier C, Desrues B, Delaval P. Clarithromycin stops lung function decline in airway-centered interstitial fibrosis.  Respiration. 2013;85(2):156-9. [pubmed]

 

PUBLICATIONS 2012

Jouan E, Le Vee M, Denizot C, Da Violante G, Fardel O. The mitochondrial fluorescent dye rhodamine 123 is a high-affinity substrate for organic cation transporters (OCTs) 1 and 2. Fundam Clin Pharmacol. 2012 Jul 24. doi: 10.1111/j.1472-8206.2012.01071.x. [Epub ahead of print] [pubmed]

Morzadec C, Bouezzedine F, Macoch M, Fardel O, Vernhet L. Inorganic arsenic impairs proliferation and cytokine expression in human primary T lymphocytes. Toxicology. 2012 Oct 9;300(1-2):46-56 [pubmed]

Kolasa E, Balaguer P, Houlbert N, Fardel O. Phorbol ester-modulation of estrogenic genomic effects triggered by the environmental contaminant benzanthracene. Toxicol In Vitro. 2012 Sep;26(6):807-16. [pubmed]

Morzadec C, Macoch M, Robineau M, Sparfel L, Fardel O, Vernhet L. Inorganic arsenic represses interleukin-17A expression in human activated Th17 lymphocytes. Toxicol Appl Pharmacol. 2012 Aug 1;262(3):217-22. [pubmed]

Fardel O, Kolasa E, Le Vee M. Environmental chemicals as substrates, inhibitors or inducers of drug transporters: implication for toxicokinetics, toxicity and pharmacokinetics. Expert Opin Drug Metab Toxicol. 2012 Jan;8(1):29-46. [pubmed]

Mayati A, Levoin N, Paris H, N’Diaye M, Courtois A, Uriac P, Lagadic-Gossmann D, Fardel O, Le Ferrec E. Induction of intracellular calcium concentration by environmental benzo(a)pyrene involves a β2-adrenergic receptor/adenylyl cyclase/Epac-1/inositol 1,4,5-trisphosphate pathway in endothelial cells. J Biol Chem. 2012 Feb 3;287(6):4041-52. [pubmed]

Lecureur V, Arzel M, Ameziane S, Houlbert N, Le Vee M, Jouneau S, Fardel O. MAPK- and PKC/CREB-dependent induction of interleukin-11 by the environmental contaminant formaldehyde in human bronchial epithelial cells. Toxicology. 2012 Feb 6;292(1):13-22. [pubmed]

Mayati A, Le Ferrec E, Lagadic-Gossmann D, Fardel O. Aryl hydrocarbon receptor-independent up-regulation of intracellular calcium concentration by environmental polycyclic aromatic hydrocarbons in human endothelial HMEC-1 cells. Environ Toxicol. 2012 Sep;27(9):556-62. [pubmed]

Gacouin A, Revest M, Letheulle J, Fillatre P, Jouneau S, Piau C, Uhel F, Tattevin P, Le Tulzo Y. Distinctive features between community-acquired pneumonia (CAP) due to Chlamydophila psittaci and CAP due to Legionella pneumophila admitted to the intensive care unit (ICU). Eur J Clin Microbiol Infect Dis. 2012 Oct;31(10):2713-8. [pubmed]

Marie I, Josse S, Decaux O, Dominique S, Diot E, Landron C, Roblot P, Jouneau S, Hatron PY, Tiev KP, Vittecoq O, Noel D, Mouthon L, Menard JF, Jouen F. Comparison of long-term outcome between anti-Jo1- and anti-PL7/PL12 positive patients with antisynthetase syndrome. Autoimmun Rev. 2012 Aug;11(10):739-45. [pubmed]

Jouneau S, Boché A, Brinchault G, Fekete K, Guillot S, Bayat S, Desrues B. On-site screening of farming-induced chronic obstructive pulmonary disease with the use of an electronic mini-spirometer: results of a pilot study in Brittany, France. Int Arch Occup Environ Health. 2012 Aug;85(6):623-30. [pubmed]

Jouneau S, Poineuf JS, Minjolle S, Tattevin P, Uhel F, Kerjouan M, Le Hô H, Desrues B. Which patients should be tested for viruses on bronchoalveolar lavage fluid? Eur J Clin Microbiol Infect Dis. 2012 Dec 14. [Epub ahead of print] [pubmed]

Lorillon G, Bergeron A, Detourmignies L, Jouneau S, Wallaert B, Frija J, Tazi A. Cladribine is effective against cystic pulmonary Langerhans cell histiocytosis. Am J Respir Crit Care Med. 2012 Nov 1;186(9):930-2. [pubmed]

 

PUBLICATIONS 2011

Moreau A, Le Vee M, Jouan E, Parmentier Y, Fardel O. Drug transporter expression in human macrophages. Fundam Clin Pharmacol. 2011 Dec;25(6):743-52.[pubmed]

Pinel-Marie ML, Louarn L, Desmots S, Fardel O, Sparfel L. Aryl hydrocarbon receptor-dependent induction of the IgA receptor FcαRI by the environmental contaminant benzo(a)pyrene in human macrophages. Toxicology. 2011 Nov 28;290(1):89-95. [pubmed]

Podechard N, Tekpli X, Catheline D, Holme JA, Rioux V, Legrand P, Rialland M, Fardel O, Lagadic-Gossmann D, Lecureur V. Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells. Toxicol Lett. 2011 Oct 30;206(3):289-99. [pubmed]

Jouneau S, Boché A, Brinchault G, Fekete K, Guillot S, Bayat S, Desrues B. On-site screening of farming-induced chronic obstructive pulmonary disease with the use of an electronic mini-spirometer: results of a pilot study in Brittany, France. Int Arch Occup Environ Health. 2011 Oct 11. [pubmed]

Bourdonnay E, Morzadec C, Fardel O, Vernhet L. Arsenic increases lipopolysaccharide-dependent expression of interleukin-8 gene by stimulating a redox-sensitive pathway that strengthens p38-kinase activation. Mol Immunol. 2011 Sep;48(15-16):2069-78. [pubmed]

Le Vee M, Jouan E, Stieger B, Lecureur V, Fardel O. Regulation of drug transporter expression by oncostatin M in human hepatocytes. Biochem Pharmacol. 2011 Aug 1;82(3):304-11. [pubmed]

Perotin JM, Jeanfaivre T, Thibout Y, Jouneau S, Lena H, Dutau H, Ramon P, Lorut C, Noppen M, Vergnon JM, Vallerand H, Merol JC, Marquette CH, Lebargy F, Deslee G. Endoscopic management of idiopathic tracheal stenosis. Ann Thorac Surg. 2011 Jul;92(1):297-301. [pubmed]

Jouneau S, Bonizec M, Belleguic C, Desrues B, Brinchault G, Galaine J, Gangneux JP, Martin-Chouly C. Anti-inflammatory effect of fluvastatin on IL-8 production induced by  Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosis. PLoS One. 2011;6(8):e22655. [pubmed]

Jouneau S, Vauléon E, Caulet-Maugendre S, Polard E, Volatron AC, Meunier C, Tattevin P, Montani D, Garin E, Raoul JL, Delaval P. ¹³¹I-labeled lipiodol-induced interstitial pneumonia: a series of 15 cases. Chest. 2011 Jun;139(6):1463-9. [pubmed]

Noble PW, Albera C, Bradford WZ, Costabel U, Glassberg MK, Kardatzke D, King TE Jr, Lancaster L, Sahn SA, Szwarcberg J, Valeyre D, du Bois RM; CAPACITY Study Group. Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials. Lancet. 2011 May 21;377(9779):1760-9. [pubmed]

Jouneau S, Khorasani N, DE Souza P, Macedo P, Zhu J, Bhavsar PK, Chung KF. EMMPRIN (CD147) regulation of MMP-9 in bronchial epithelial cells in COPD. Respirology. 2011 May;16(4):705-12. doi: 10.1111/j.1440-1843.2011.01960.x. [pubmed]

Martin-Chouly C, Morzadec C, Bonvalet M, Galibert MD, Fardel O, Vernhet L. Inorganic arsenic alters expression of immune and stress response genes in activated primary human T lymphocytes. Mol Immunol. 2011 Mar;48(6-7):956-65. [pubmed]

Gilot D, Le Meur N, Giudicelli F, Le Vée M, Lagadic-Gossmann D, Théret N, Fardel O. RNAi-based screening identifies kinases interfering with dioxin-mediated up-regulation of CYP1A1 activity. PLoS One. 2011 Mar 29;6(3):e18261. [pubmed]

Hervier B, Uzunhan Y, Hachulla E, Benveniste O, Nunes H, Delaval P, Musset L, Dubucquoi S, Wallaert B, Hamidou M. Antisynthetase syndrome positive for anti-threonyl-tRNA synthetase (anti-PL7) antibodies. Eur Respir J. 2011 Mar;37(3):714-7. [pubmed]

Kerjouan M, Jouneau S, Lena H, Luraine R, Desrues B, Delaval P. Pulmonary sarcoidosis developing during treatment with etanercept. Rev Mal Respir. 2011 Mar;28(3):360-4. [Article in French].[pubmed]

Mayati A, Le Ferrec E, Lagadic-Gossmann D, Fardel O. Aryl hydrocarbon receptor-independent up-regulation of intracellular calcium concentration by environmental polycyclic aromatic hydrocarbons in human endothelial HMEC-1 cells. Environ Toxicol. 2011. Feb 22. doi: 10.1002/tox.20675. [pubmed]

Péry AR, Brochot C, Desmots S, Boize M, Sparfel L, Fardel O. Predicting in vivo gene expression in macrophages after exposure to benzo(a)pyrene based on in vitro assays and toxicokinetic/toxicodynamic models. Toxicol Lett. 2011 Feb 25;201(1):8-14. [pubmed]

Le Vee M, Jouan E, Moreau A, Fardel O. Regulation of drug transporter mRNA expression by interferon-γ in primary human hepatocytes. Fundam Clin Pharmacol. 2011 Feb;25(1):99-103. doi: 10.1111/j.1472-8206.2010.00822.x. [pubmed]

Vergnenegre A, Corre R, Berard H, Paillotin D, Dujon C, Robinet G, Crequit J, Bota S, Thomas P, Chouaid C; 0506 GFPC Team. Cost-effectiveness of second-line chemotherapy for non-small cell lung cancer: an economic, randomized, prospective, multicenter phase III trial comparing docetaxel and pemetrexed: the GFPC 05-06 study. J Thorac Oncol. 2011 Jan;6(1):161-8. [pubmed]