To call up the publications in PubMed click on : Michel Samson, Philippe Gripon, Jacques Le Seyec, Jean-Pierre Gangneux, Christian Michelet, Claire Piquet-Pellorce, Laurence Amiot, Florence Robert-Gangneux.

ID Researcher for each researcher :

SAMSON  Michel  : F-8356-2013
LE SEYEC Jacques : J-5680-2015
GRIPON Philippe : J-6068-2015
PIQUET-PELLORCE Claire : I-4195-2015
GANGNEUX Jean-Pierre : J-2960-2015
ROBERT-GANGNEUX Florence : I-4692-2015
AMIOT Laurence : J-5955-2015
DIMANCHE-BOITREL Marie-Thérèse : I-4642-2015
RAGUENES-NICOL Céline: I-2693-2015
THIBAULT Vincent : J-7193-2015
GUILLET Benoit : J-7830-2015
DION Sarah : I-5656-2015

2015  (last updated 27 January 2016)

Rivière L, Gerossier L, Ducroux A, Dion S, Deng Q, Michel ML, Buendia MA, Hantz O, Neuveut C. HBx relieves chromatin-mediated transcriptional repression of hepatitis B viral cccDNA involving SETDB1 histone methyltransferase. J Hepatol. 2015 Nov;63(5):1093-102.

Martin P, Dubois C, Jacquier E, Dion S, Mancini-Bourgine M, Godon O, Kratzer R, Lelu-Santolaria K, Evlachev A, Meritet JF, Schlesinger Y, Villeval D, Strub JM, Van Dorsselaer A, Marchand JB, Geist M, Brandely R, Findeli A, Boukhebza H, Menguy T, Silvestre N, Michel ML, Inchauspé G. TG1050, an immunotherapeutic to treat chronic hepatitis B, induces robust T cells and exerts an antiviral effect in HBV-persistent mice. Gut. 2015 Dec;64(12):1961-71.

Ruff M, Leyme A, Le Cann F, Bonnier D, Le Seyec J, Chesnel F, Fattet L, Rimokh R, Baffet G, Théret N. The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition. Plos One. 2015 25;10(9):e0139179.

Bleau C, Filliol A, Samson M and Lamontagne L. Brain invasion by mouse hepatitis virus depends on impairment of tight junctions and interferon- production in brain microvascular endothelial cells. J Virol. 2015. ;89(19):9896-908. IF=4.439

Basset L, Chevalier S, Danger Y, Arshad MI, Piquet-Pellorce C, Gascan H and Samson M. Interleukin-27 and IFNγ regulate the expression of CXCL9, CXCL10 and CXCL11 in hepatitis. J Mol Med. 2015 ; 93(12):1355-67. IF=5.107

Bourreau E, Ginouves M, Prévot G, Hartley MA, Gangneux JP, Robert-Gangneux F, Dufour J, Sainte Marie D, Bertolotti A, Pratlong F, Martin R, Schütz F, Couppié P, Fasel N, Ronet C. Leishmania-RNA virus presence in L. guyanensis parasites increases the risk of firstline treatment failure and symptomatic relapse. J Infect Dis, 2015 in press. IF=5,778

Martin-Blondel G, Iriart X, El Baidouri F, Simon S, Mills D, Demar M, Pistone T, Le Taillandier T, Malvy D, Gangneux JP, Couppie P, Munckhof W, Marchou B, Ravel C, Berry A. Outbreak of Leishmania braziliensis Cutaneous Leishmaniasis, Saül, French Guiana. Emerg Infect Dis 2015;21(5):892-4. IF=7,327

Cabezas Y, Legentil L, Robert-Gangneux F, Daligault F, Belaz S, Nugier-Chauvin C, Tranchimand S, Tellier C, Gangneux JP, Ferrières V. Leishmania cell wall as potent targets for antiparasitic drugs. A focus on the glycoconjugates. Organic and Biomolecular chemistry, in press. IF=3,487

Belaz S, Rattier T, Lafite P, Moreau P, Routier F, Robert-Gangneux F, Gangneux JP, Daniellou R. Identification, biochemical characterization, and in-vivo expression of the intracellular invertase BfrA from the pathogenic parasite Leishmania major. Carbohyd Res, in press. IF=1,929

Arshad MI*, Guihard P*, Danger Y, Noel G, Le Seyec J, Boutet MA, Richards CD, L’Helgoualc’h A, Genet V, Lucas-Clerc C, Gascan H, Blanchard F, Piquet-Pellorce C and Samson M. Oncostatin M induces IL-33 expression in liver endothelial cells in mice and expands ST2+CD4+ lymphocytes. Am J Physiol Gastrointest Liver Physiol. * contributed equally. 2015. In press. IF=3.798

Amiot L, Vu N and Samson M. Biology of the immunomodulatory molecule HLA-G in human liver diseases. J Hepatol. 2015, Jun;62(6):1430-1437.Review. IF=11,336

Arshad MI, Piquet-Pellorce C, Filliol A, L’ Helgoualc’h A, Lucas-Clerc C, Jouan- Lanhouet S, Dimanche-Boitrel MT and Samson M. The chemical inhibitors of cellular death, PJ34 and necrostatin-1, down-regulated the cytokine IL-33 expression in liver. J Mol Med. 2015, 93(8):867-78. IF=5.107

Bastien P, Volf P, Depaquit J, Dondji B, Gallego M, Gangneux JP, Izri A, Marty P, Piarroux R, Pratlong F, Dedet JP. Comments about the presence of Leishmania major in gorillas’ feces. J Infect Dis. 2015, 212(3):505-6. REVIEW. IF=5,778

Bouezzedine F, Fardel O and Gripon P. Interleukin 6 inhibits HBV entry through NTCP down regulation. Virology. 2015, 481:34-42. IF=3,321

Kim JH, Gripon P, Bouezzedine F, Jeong MS, Chi SW, Ryu SE, Hong HJ. Enhanced humanization and affinity maturation of neutralizing anti-hepatitis B virus preS1 antibody based on antigen-antibody complex structure. FEBS Lett. 2015, 589(2):193-200. IF=3,169

Rostan O, Arshad MI, Piquet-Pellorce C, Robert-Gangneux F, Gangneux JP and Samson M. Crucial and diverse role of IL-33/ST2 axis in infectious diseases. Infect Immun. 2015, 83(5):1738-48. REVIEW. IF=3.731

Vu TH, Le Lamer AC, Lalli C, Boustie J, Samson M, Lohézic-Le Dévéhat F, Le Seyec J. Depsides: lichen metabolites active against hepatitis C virus. Plos One. 2015, 10(3):e0120405. IF=3.234


Amiot L, Vu N and Samson M. Immunomodulatory properties of HLA-G in infectious diseases. J Immunol Res. 2014. 2014:298569. REVIEW.

Amiot L, Vu N, Rauch M, L’ Helgoualc’h A, Chalmel F, Gascan H, Turlin B, Guyader D and Samson M. Expression of HLA-G by mast cells is associated with hepatitis C virus induced liver fibrosis. J. Hepatol. 2014. 60(2):245-52. IF=11,336

Aymami M, Revest M, Piau C, Chabanne C, Le Gall F, Lelong B, Verhoye JP, Michelet C, Tattevin P, Flécher E. Heart transplantation as salvage treatment of intractable infective endocarditis. Clin Microbiol Infec. 2014 Dec 11. pii: S1198-743X(14)00114-1. IF= 5.768
Cotte L, Braun J, Lascoux-Combe C, Vincent C, Valantin MA, Sogni P, Lacombe K, Neau D, Aumaitre H, Batisse D, de Truchis P, Gervais A, Michelet C, Morlat P, Vittecoq D, Rosa I, Bertucci I, Chevaliez S, Aboulker JP, Molina JM; French National Agency for Research on AIDS and Viral Hepatitis (ANRS) HC26 Study Group. Telaprevir for HIV/hepatitis C virus-coinfected patients failing treatment with pegylated interferon/ribavirin (ANRS HC26 TelapreVIH) : an open-label, single-arm, phase 2 trial. Clin Infect Dis. 2014 59(12):1768-76. IF=8.886
Florimond A, Chouteau P, Bruscella P, Le Seyec J, Mérour E, Ahnou N, Mallat A, Lotersztajn S, Pawlotsky JM. Human hepatic stellate cells are not permissive for hepatitis C virus entry and replication. Gut. 2014, gutjnl-2013-305634. IF=14,660
Ilboudo A, Nault JC, Dubois-Pot-Schneider H, Corlu A, Zucman-Rossi J, Samson M and Le Seyec J. Overexpression of phosphatidylinositol 4-kinase type IIIalpha is associated with undifferentiated status and poor prognosis of human hepatocellular carcinoma. BMC Cancer. 2014. 14(1):7. IF=3,362
Lagarrigue M, Lavigne R, Tabet E, Genet V, Thomé JP, Rondel K, Guével B, Multigner L, Samson M and Pineau C. Localization and in situ absolute quantification of chlordecone in the mouse liver by MALDI imaging. Anal Chem 2014 86(12):5775-83. IF= 5,636
Suleman M, Gangneux JP, Legentil L, Belaz S, Cabezas Y, Manuel C, Dureau R, Sergent O, Burel A, Daligault F, Ferrières V, Robert-Gangneux F. Alkyl galactofuranosides strongly interact with Leishmania donovani membrane and provide anti-leishmanial activity. Antimicrob Agents Ch, 2014, 58(4):2156-2166. IF=4,476
Tattevin P, Revest M, Lefort A, Michelet C, Lortholary O. Fungal endocarditis: current challenges. Int J Antimicrob Ag. 2014 44(4):290-4. IF=4,296
Verdier MC, Patrat-Delon S, Lemaitre F, Revest M, Rivalan J, Michelet C, Bellissant E. Suspicion of interaction between maribavir and everolimus in a renal transplant recipient. Transplantation. 2014 8(3):e20-1. IF=3,828
Arshad MI, Patrat-Delon S, Piquet-Pellorce C, L’Helgoualc’h A, Rauch M, Lucas-Clerc C, Bleau C, Lamontagne L and Samson M. Pathogenic mouse hepatitis virus or Poly(I:C) induce IL-33 in hepatocytes in murine models of hepatitis. PLoS ONE. 2013; 8(9):e74278. [Pubmed].

Rostan O, Gangneux JP, Piquet-Pellorce C, Manuel C, McKenzie A, Guiguen C, Samson M and Robert-Gangneux F. IL-33/ST2 axis is associated with human visceral leishmaniasis and suppresses Th1 responses in the liver of BALB/c mice infected with Leishmania donovani. mBio. [Pubmed].
Gangneux JP, Poinsignon Y, Donaghy L, Amiot L, Tarte K, Mary C, Robert-Gangneux F. Indoleamine 2,3-dioxygenase activity as a potential biomarker of immune suppression during visceral leishmaniasis. Innate Immun. 2013 Feb 14. [Pubmed]
Rostan O, Robert-Gangneux F, Lambert M, Samson M and Gangneux JP. Human hepatic stellate cells in primary culture are safe targets for Leishmania donovani. Parasitology. 2013 Apr;140(4):471-81. [Pubmed]
MI Arshad, C Piquet-Pellorce, A L’Helgoualc’h, M Rauch, S Patrat-Delon, F Ezan, C Lucas-Clerc, S Nabti, A Lehuen, FJ Cubero, C Trautwein and M Samson. TRAIL, but not FasL and TNFα, regulates IL-33 expression in hepatocytes during acute hepatitis in mice. Hepatology. 2012. Dec;56(6):2353-62.  [Pubmed]
Jouan-Lanhouet S, Arshad MI, Piquet-Pellorce C, Martin-Chouly C, Le Moigne-Muller G, Van Herreweghe F, Takahashi N, Sergent O, Lagadic-Gossmann D, Vandenabeele P, Samson M and Dimanche-Boitrel MT. TRAIL induces necroptosis involving RIPK1/ RIPK 3-dependent PARP-1 activation. Cell Death Differ. 2012. Dec;19(12):2003-14. [Pubmed]
Arshad MI, Piquet-Pellorce C and Samson M.  IL-33 and HMGB1 alarmins: sensors of cellular death and their involvement in liver pathology. Liver international. Sep;32(8):1200-10. [Pubmed]

Frémin C, Ezan F, Guegan JP, Gailhouste L, Trotard M, Le Seyec J, Rageul J, Theret N, Langouët S, Baffet G. The complexity of ERK1 and ERK2 MAPKs in multiple hepatocyte fate responses. J Cell Physiol. 2012 Jan;227(1):59-69. [Pubmed]
Robert-Gangneux F, Drogoul AS, Rostan O, Piquet-Pellorce C, Cayon J, Lisbonne M, Herbelin A, Gascan H, Guiguen C, Samson M and Gangneux JP. Invariant NKT cells drive hepatic cytokinic microenvironment favoring efficient granuloma formation and early control of Leishmania donovani infection. PLoS ONE. 2012;7(3):e33413. [Pubmed]Monnier J, Boissan M, L’Helgoualc’h A, Lacombe ML, Turlin B, Zucman-Rossi J, Théret N, Piquet-Pellorce C and Samson M. CXCR7 is up-regulated in human and murine hepatocellular carcinoma and is specifically expressed by endothelial cells.  Eur J Cancer. 2012 Janv;48(1):138-48. [Pubmed]Bidart M, Ricard N, Levet S, Samson M, Mallet C, David L, Subileau M, Tillet E, Feige JJ, Bailly S. BMP9 is produced by hepatocytes and circulates mainly in an active mature form complexed to its prodomain. Cell Mol Life Sci. 2012 Jan;69(2):313-24. Jun 28. [Pubmed]2011Bourd-Boittin K, Bonnier D, Leyme A, Mari B, Tuffery P, Samson M, Ezan F, Baffet G, Theret N. Protease profiling of liver fibrosis reveals the adam metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of TGF-β.  Hepatology. 2011 Dec;54(6):2173-84.  [Pubmed]Jouneau S, Bonizec M,  Belleguic C, Roux PF, Desrues B, Brinchault G, Galaine J, Gangneux JP and  Martin-Chouly C. Anti-inflammatory effect of fluvastatin on IL-8 production induced by Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosis. PloS One.  2011;6(8):e22655. [Pubmed]Le Goffic R, Leymarie O, Chevalier C, Rebours E, Da Costa B, Jasmina V, Descamps D, Sallenave JM, Rauch M, Samson M and Delmas B. PB1-F2 expression amplifies the host response magnitude during influenza virus infection. PloS Pathog. Aug;7(8):e1002202. [Pubmed]Lortholary O, Gangneux JP, Sitbon K, Lebeau B, de Monbrison F, Le Strat Y, Coignard B, Dromer F, Bretagne S; for the French Mycosis Study Group. Epidemiological trends in invasive aspergillosis in France: the SAIF network (2005-2007). Clin Microbiol Infect. 2011 Dec;17(12):1882-9. [pubmed]
Michallet M, Gangneux JP, Lafuma A, Herbrecht R, Ribaud P, Caillot D, Dupont B, Moreau P, Berger P, O’Sullivan AK. Cost effectiveness of posaconazole in the prophylaxis of invasive fungal infections in acute leukaemia patients for the French healthcare system. J Med Econ. 2011;14(1):28-35. Epub 2010 Dec 23. [pubmed]Frémin C, Ezan F, Guegan JP, Gaillouste L, Trotard M, Seyec JL, Theret N, Langouët S, Baffet G. The complexity of ERK1 and ERK2 MAPKs in multiple hepatocyte fate responses. J Cell Physiol. 2011 Mar 24. doi: 10.1002/jcp.22742. [pubmed]Massé J, Piquet-Pellorce C, Viet J, Guerrier D, Pellerin I, Deschamps S. ZFPIP/Zfp462 is involved in P19 cell pluripotency and in their neuronal fate. Exp Cell Res. 2011 Aug 1;317(13):1922-34. Epub 2011 May 5. PMID: 21570965Tauzin S, Chaigne-Delalande B, Selva E, Khadra N, Daburon S, Contin-Bordes C, Blanco P, Le Seyec J, Ducret T, Counillon L, Moreau JF, Hofman P, Vacher P, Legembre P. The Naturally Processed CD95L Elicits a c-Yes/Calcium/PI3K-Driven Cell Migration Pathway. PLoS Biol. 2011 Jun;9(6):e1001090. Epub 2011 Jun 21. PMID: 21713032

Boudot A, Kerdivel G, Habauzit D, Eeckhoute J, Le Dily F, Flouriot G, Samson M, Pakdel F. Differential Estrogen-Regulation of CXCL12 Chemokine Receptors, CXCR4 and CXCR7, Contributes to the Growth Effect of Estrogens in Breast Cancer Cells. PLoS One. 2011;6(6):e20898. Epub 2011 Jun 10. PMID: 21695171

Le Goffic R, Arshad MI, Rauch M, L’helgoualc’h A, Delmas B, Piquet-Pellorce C, Samson M. Influenza Virus Infection Induces IL-33 in Mouse Lungs. Am J Respir Cell Mol Biol. 2011 Jun 3. PMID: 21642589

Arshad MI, Rauch M, L’helgoualc’h A, Julia V, Leite-de-Moraes MC, Lucas-Clerc C, Piquet-Pellorce C, Samson M. NKT cells are required to induce high IL-33 expression in hepatocytes during ConA-induced acute hepatitis. Eur J Immunol. 2011 May 10. doi: 10.1002/eji.201041332.  PMID: 21557213+ cover Letter

Lisbonne M, L’helgoualc’h A, Nauwelaers G, Turlin B, Lucas C, Herbelin A, Piquet-Pellorce C, Samson M.Invariant natural killer T-cell-deficient mice display increased CCl(4) -induced hepatitis associated with CXCL1 over-expression and neutrophil infiltration. Eur J Immunol. 2011 Jun;41(6):1720-32. doi: 10.1002/eji.201041006. PMID: 21469102

Robert-Gangneux F, Gangneux JP, Vu N, Jaillard S, Guiguen C, Amiot L. High level of soluble HLA-G in amniotic fluid is correlated with congenital transmission of Toxoplasma gondii. Clin Immunol. 2011 Feb;138(2):129-34. Epub 2010 Dec 24. PMID: 21185786

Amiot L, Ferrone S, Grosse-Wilde H, Seliger B. Biology of HLA-G in cancer: a candidate molecule for therapeutic intervention? Cell Mol Life Sci. 2011 Feb;68(3):417-31. Review. PMID: 21063893