Check back frequently for updates on Master, PhD and postdoctoral projects.
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Enseignement : La personne recruté(e) effectuera son service d’enseignement au sein de l’équipe pédagogique de Physiologie Animale et Neurosciences. Elle devra posséder la maîtrise des concepts de la physiologie moléculaire et intégrative. Elle devra être force de proposition dans la conception de nouveaux enseignements au sein du Master BAS ainsi que dans la mise en place de modules de formation à visée internationale.
Composante d’enseignement : UFR SVE, Université de Rennes1
Lieu d’exercice : Equipe pédagogique de Physiologie Animale et Neurosciences
Nom directeur: Pascal Benquet
Tel directeur : 02 23 23 52 37
Email directeur. : pascal.benquet@univ-rennes1.fr
URL. : http://www.sve.univrennes1.fr/internet/Formations/Disciplines/PhysiologieAnimale/
Recherche :
Le/la professeur(e) devra mettre en œuvre son propre programme de recherche dans le domaine de la physiologie intégrative et comparée, dans le champ du développement et du fonctionnement normal et pathologique (perturbation endocrinienne notamment) des circuits endocriniens. Il/elle devra maîtriser des approches innovantes de type moléculaires (omics), cellulaires (imagerie notamment) et être familier(e) avec les approches de la transgénèse.
Le /la professeur(e) occupera une place majeure dans l’évolution des activités de l’équipe NEED (Neuroendocrine Effects of Endocrine Disruptors) récemment labellisée par l’Inserm dans le cadre de la création de l’IRSET (Institut de Recherche en Santé, Environnement et Travail, Inserm U1085) http://biosit.univ-rennes1.fr/unites/U1085_Irset/.
Lieu d’exercice : Equipe NEED, IRSET – Inserm U1085
Nom responsable équipe de recherche: Olivier Kah (Responsable de l’équipe NEED)
Tel responsable équipe de recherche: 02 23 23 67 65
Email responsable équipe de recherche: olivier.kah@univ-rennes1.fr
URL équipe de recherche: http://www.irset.org/?page_id=240
Nom du responsable de l’UMR IRSET (Inserm U1085) : Bernard Jégou
Tel responsable de l’UMR IRSET (Inserm U1085) : 02 23 23 69 11
Email responsable de l’UMR IRSET (Inserm U1085) : bernard.jegou@inserm.fr
URL équipe de recherche: http://www.irset.org/?page_id=240
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Postdoctoral position in cell death signaling- Molecular mechanisms of TRAIL-induced necroptosis
A 36 month post-doctoral position (starting in january 2013) is available at the Research Institute in Health, Environment and Labor in Rennes to work with Marie-Thérèse Dimanche-Boitrel. The project will focused on molecular mechanisms regulating TRAIL-induced necroptosis (see Jouan-Lanhouet et al., Cell Death Differ 2012 Jul 20. doi: 10.1038/cdd.2012.90. [Epub ahead of print] and references therein).
Candidates should have a scientific background and interest in death receptors signaling pathways. Experience of molecular biology and biochemistry is essential. Experience for protein purification by TAP-tag and proteomics analysis would be desirable.
For further information and applications, contact:
Marie-Thérèse DIMANCHE-BOITREL, PhD,
Directeur de recherche à l’INSERM
IRSET/INSERM UMR 1085
Faculté de Pharmacie
2 avenue du Pr Léon Bernard
35043 Rennes cedex
France
Email : marie-therese.boitrel@univ-rennes1.fr, marie-therese.boitrel@inserm.fr
Phone : 33 2 23 23 48 99
Web site : http://www.irset.org/?page_id=358
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POST-DOCTORAL POSITION IN VIROLOGY
The research group “Viral and Chemical Environment & Reproduction” lead by Nathalie Dejucq-Rainsford targets an important part of its research into the better understanding of the interactions between HIV and the male genital tract. Over 60 million people have been infected by HIV-1 over the past 25 years, most through exposure to contaminated semen, and increased knowledge of the mechanisms of transmission is required to facilitate the development of new approaches for prevention. Semen contains both HIV free particles and infected cells. However, the origin, nature and contribution to transmission of cell-associated HIV remain ill defined. The aim of the present project is to provide critical information about both the origin of HIV in semen and the role of semen in modulating HIV/SIV sexual transmission, to promote the discovery of new HIV prevention strategies. The project benefits from a network of collaborators in France and in the US and state-of- the art research facilities within our 200 person-research institute (IRSET).
Position: 2-year post-doctoral fellowship (starting September, 2012).
Profile: the sucessful candidate will have a solid background in virology (HIV), cell culture and molecular biology techniques. Knowledge of the immunology of the reproductive tract will be an asset. This is a unique opportunity for a young scientist to develop studies aimed at understanding the mechanisms of HIV transmission. The post-doctoral researcher will be in charge of experiments for deciphering the origin of HIV/SIV in semen and analyzing the modulating effect of human semen on cell-associated transmission using original approaches (cell and tissue cultures).
Required technical skills include long standing cell culture experience, experience of manipulating HIV in a cat3 lab, HIV production and assays, immunohistochemistry/ in situ hybridization, flow cytometry, molecular biology techniques (quantitative PCR…).
Location: University of Rennes 1, Irset (Institut de recherche en sante, environnement et travail) Rennes, France. Rennes, capital city of Brittany, combines high-level research laboratories, state-of-the-art research facilities and a unique quality of life in a renowned cultural setting. Irset scientists closely interact with the University Hospital Rennes and they have access to core platforms and services provided by Biogenouest. Irset was founded and positively evaluated by AERES in 2011 and has been certified as a research institute by Inserm for the period of 2012-2017. Irset is a joint project of the EHESP Public School of Health in Rennes, Inserm and the University of Rennes 1. Outstanding postdoctoral students are encouraged to apply for research positions at France’s universities (lecturer) or Inserm and CNRS research institutes (Chargé de Recherche) that offer various support programs (Avenir/Atip/Chair d’excellence) for promising researchers.
Application: please send a CV, description of past research and experience, list of publications, two references, and expected availability date to Nathalie Dejucq-Rainsford.
E-mail: nathalie.dejucq-rainsford@inserm.fr
Phone: +33 (0) 2 23 23 50 69